Clostridium difficile is a gastrointestinal bacterial pathogen that got its name because it causes an infection in humans that can be difficult to treat. There is a lot of evidence that many cases of C. difficile arise from antibiotics destabilizing the microbiome. Antibiotics have a cost, and that cost is sometimes meted out in the health of the patients who take those antibiotics; sometimes, as they say, the cure is worse than the disease. answer some of the following questions to discuss:
In your opinion, are antibiotics worth it? Why or why not? After all, they have caused some serious problems, like C. difficile. Consider society without any antimicrobial drug access: would we be where we are today without them? Where would we be if, suddenly, all antibiotics went away today? How do we find a balance in using antibiotics enough, but not too much? Cite specific antimicrobial drugs to support your answer.
Research and choose one alternative treatment for C. difficile, or for the health of the microbiome as a whole. What is the mechanism by which that treatment affects change in the human gut? What is happening at the microbial level (to the best of your knowledge)? Is there sufficient evidence for what is supposed to be happening? Or is there some question as to the alternative treatments efficacy?
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