Discuss a current scientific concept or idea, from the past 10 years, that is still considered emerging or experimental. If evidence were to overwhelmingly support this new concept or idea, how might it affect the scientific discipline, and society as a whole?

Discuss a current scientific concept or idea, from the past 10 years, that is still considered emerging or experimental. If evidence were to overwhelmingly support this new concept or idea, how might it affect the scientific discipline, and society as a whole?

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My discipline: Natural Science

I WANT TO TALK ABOUT LIQUID BIOPSIES AS MY TOPIC

My topic: Liquid Biopsies
(DEFINITION/EXTRA INFORMATION) Promised to detect cancer earlier than other traditional methods, customize treatments through genotyping, and measure minimal lasting strands of the disease after treatment. The procedure is less invasive as it can detect tumors through blood and has less risk to the patient. (TLDR: This could help patients that have issues or cannot go into surgery and give them specific treatment plans and therapy depending on their needs and can detect recurrence.) MCED tests- detect 50+ cancers w/ a blood test. Test for proteins found in cancerous cells. Helps with early detections of cancers, instead of when it’s become harder to fight off.

Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical oncology, offering ease in tumor sampling, continuous monitoring by repeated sampling, devising personalized therapeutic regimens, and screening for therapeutic resistance. Liquid biopsies consist of isolating tumor-derived entities like circulating tumor cells, circulating tumor DNA, tumor extracellular vesicles, etc., present in the body fluids of patients with cancer, followed by an analysis of genomic and proteomic data contained within them. Methods for isolation and analysis of liquid biopsies have rapidly evolved over the past few years as described in the review, thus providing greater details about tumor characteristics such as tumor progression, tumor staging, heterogeneity, gene mutations, and clonal evolution, etc. Liquid biopsies from cancer patients have opened up newer avenues in detection and continuous monitoring, treatment based on precision medicine, and screening of markers for therapeutic resistance. Though the technology of liquid biopsies is still evolving, its non-invasive nature promises to open new eras in clinical oncology. The purpose of this review is to provide an overview of the current methodologies involved in liquid biopsies and their application in isolating tumor markers for detection, prognosis, and monitoring cancer treatment outcomes.

LINKS TO HELP WITH RESEARCH
https://doaj.org/article/821ca62ca1814c9795edb97bf3240208
https://doaj.org/article/3c5818146620492eaf38c165359690a8
https://doaj.org/article/f5f111fcf0c14b51a2075cd515f8e3a1
https://pubmed.ncbi.nlm.nih.gov/35303879/

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